Job ID: 137467015

Job Summary
Employment Type
Full Time
Years Experience
1 - 3 years
Job Description

The Keck Center for Transgene Research at the University of Notre Dame is in the process of hiring two postdoctoral fellows.


One position is for a protein biochemist.  The main focus of this position will be in studying structure/function requirements for interactions of Group A streptococcus (GAS) proteins with human host proteins.  This will require generating, purifying, and characterizing recombinant proteins and peptides.  Further characterization will require the use of surface plasmon resonance, ELISAs, SDS-PAGE and Western blotting, calorimetry, analytical ultracentrifugation, circular dichroism, and other related instrumentations for characterizing proteins and their interactions. The candidate should be willing to learn and perform other related duties.


The second postdoctoral position is for an animal physiologist/pathologist.  This will involve in vivo analyses of GAS infection.  Studies will involve histology and immunohistochemistry of murine tissue, blood- and tissue-based ELISA and functional analyses monitoring changes in hemostasis, inflammation, and complement.  Some hands-on experience with flow cytometry and cell sorting is preferred.


Requirements for both positions:
Doctoral degree in Biochemistry or related discipline.  Optimally, the successful candidate would have a strong background in biochemistry, protein expression, molecular biology, cell biology, animal physiology, or related fields.

Interested candidates should send their curriculum vitae, a statement of research goals, and 3 letters of recommendation to:


Victoria A. Ploplis, Ph.D.
Associate Director
W. M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall
University of Notre Dame
Notre Dame, Indiana 46556
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University of Notre Dame

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