Bioinformatics Scientist
Spectraforce Technologies
United States, Massachusetts, Cambridge
Jun 09, 2025
Bioinformatics Scientist
23 months
Cambridge, MA 02141
Qualifications:
Required Qualifications:
* Ph.D. in Computational Biology or a related field.
* A proven track record of over 3 years in multi-omics analysis.
* Fundamental understanding of statistical methods and multi-omics data analysis and integration (e.g., RNA-Seq, single-cell RNA-Seq, genotype, spatial transcriptomics, OLINK).
* Proficiency in R, Python, and Bash, with the ability to establish best practices for reproducible data analyses.
* Experience with high-performance computing (HPC) systems and AWS Cloud Computing (e.g., IAM, S3 buckets).
* A collaborative and self-motivated individual with a strong work ethic, capable of managing multiple objectives in a dynamic environment and adapting to changing priorities.
* Excellent written and verbal communication skills.
Preferred Qualifications:
* Experience in processing and analyzing real-world data.
* Familiarity with spatial transcriptomics analysis.
* Knowledge of statistical and population genetics principles.
Responsibilities:
Location: Cambridge, MA
Department: Data and Genome Sciences
Group: Precision Genetics
The Precision Genetics group within the Data and Genome Sciences Department is seeking a skilled Contractor to join our Computational Precision Immunology team. We are looking for a data scientist with extensive experience in multi-modal and multi-scale data analyses to contribute to our innovative research efforts.
Key Responsibilities:
* Data Ingestion: Query external databases to acquire relevant multi-omics datasets (e.g., PubMed, Gene Expression Omnibus, ArrayExpress, gnomAD, GTEx, Ensembl).
* RNA-seq Analysis: Perform quality control (QC) and analysis of bulk and single-cell RNA-seq data using state-of-the-art methods (e.g., FastQC, STAR, Limma, DESeq2, clusterProfiler, Seurat, scanpy, LeafCutter).
* Multi-Omics Analysis: Analyze diverse molecular data types including spatial transcriptomics (e.g., Slide-seq, MERFISH, squidpy) and proteomics (e.g., OLINK, mass spectrometry-based approaches).
* Data Integration: Integrate multi-omics datasets, including gene/protein expression, mRNA splicing, spatial transcriptomics, and genotype data.
* Documentation: Prepare detailed documentation of analysis methods and results in a timely manner.
Key Skills:
* Required expertise with multi-omics data analysis and integration (e.g., RNA-Seq, single-cell RNA-Seq)
* Transcriptomics analysis.
* Proficiency in R and Bash.
* High-performance computing (HPC) systems and AWS Cloud Computing (e.g., IAM, S3 buckets).
Spectraforce Technologies
United States, Massachusetts, Cambridge
Jun 09, 2025
Bioinformatics Scientist
23 months
Cambridge, MA 02141
Qualifications:
Required Qualifications:
* Ph.D. in Computational Biology or a related field.
* A proven track record of over 3 years in multi-omics analysis.
* Fundamental understanding of statistical methods and multi-omics data analysis and integration (e.g., RNA-Seq, single-cell RNA-Seq, genotype, spatial transcriptomics, OLINK).
* Proficiency in R, Python, and Bash, with the ability to establish best practices for reproducible data analyses.
* Experience with high-performance computing (HPC) systems and AWS Cloud Computing (e.g., IAM, S3 buckets).
* A collaborative and self-motivated individual with a strong work ethic, capable of managing multiple objectives in a dynamic environment and adapting to changing priorities.
* Excellent written and verbal communication skills.
Preferred Qualifications:
* Experience in processing and analyzing real-world data.
* Familiarity with spatial transcriptomics analysis.
* Knowledge of statistical and population genetics principles.
Responsibilities:
Location: Cambridge, MA
Department: Data and Genome Sciences
Group: Precision Genetics
The Precision Genetics group within the Data and Genome Sciences Department is seeking a skilled Contractor to join our Computational Precision Immunology team. We are looking for a data scientist with extensive experience in multi-modal and multi-scale data analyses to contribute to our innovative research efforts.
Key Responsibilities:
* Data Ingestion: Query external databases to acquire relevant multi-omics datasets (e.g., PubMed, Gene Expression Omnibus, ArrayExpress, gnomAD, GTEx, Ensembl).
* RNA-seq Analysis: Perform quality control (QC) and analysis of bulk and single-cell RNA-seq data using state-of-the-art methods (e.g., FastQC, STAR, Limma, DESeq2, clusterProfiler, Seurat, scanpy, LeafCutter).
* Multi-Omics Analysis: Analyze diverse molecular data types including spatial transcriptomics (e.g., Slide-seq, MERFISH, squidpy) and proteomics (e.g., OLINK, mass spectrometry-based approaches).
* Data Integration: Integrate multi-omics datasets, including gene/protein expression, mRNA splicing, spatial transcriptomics, and genotype data.
* Documentation: Prepare detailed documentation of analysis methods and results in a timely manner.
Key Skills:
* Required expertise with multi-omics data analysis and integration (e.g., RNA-Seq, single-cell RNA-Seq)
* Transcriptomics analysis.
* Proficiency in R and Bash.
* High-performance computing (HPC) systems and AWS Cloud Computing (e.g., IAM, S3 buckets).
Job ID: 480947565
Originally Posted on: 6/12/2025
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