Scientist II/Senior Scientist, Protein Science
- Hexagon Bio
- Menlo Park, California
- Full Time
15 years hands-on industry experience in protein science is required. Sr. Scientist : PhD in Molecular Biology, Biochemistry, Structural Biology, Immunology, or a related field with > 8 years industry experience in protein science or antibody / protein engineering. Thorough understanding of antibody structure and protein biochemistry best practices. Demonstrated experience with molecular biology techniques, including DNA construct design, PCR, DNA purification and molecular cloning is required. Demonstrated experience with sterile technique and suspension cell culture for protein production is required. Demonstrated expertise with AKTA systems and Unicorn software is required. Significant knowledge and hands-on experience in analytical methods (such as HPLC, aSEC, IEX, HIC, LCMS, SDS-PAGE, ce-SDS, ce-IEF, HCP and endotoxin detection) is required. Experience with gram scale antibody production and purification and/or experience with antibody-drug conjugate (ADC) technologies, including familiarity with linker-payload strategies, conjugation methods, and biophysical and functional evaluation of ADCs is highly desired. Experience with target binding assays, developability assessments and/or CRO management is a plus. Strong desire to continue seeking new technological innovations supporting laboratory work. Excellent analytical and problem-solving skills, with the ability to troubleshoot experiments and propose innovative solutions. Effective communication and collaboration skills, with the ability to work independently and as part of a multidisciplinary research team. Self-motivation, initiative and boldness to dive into a fast-paced new startup. What We Offer: A flexible and dynamic work environment where you pave your own path, Hexagon cultivates employees' unique strengths at all levels and provides mobility across departments. "All Hands Meetings" provide an opportunity to share company and team updates. These meetings are rooted in our value of transparency. They are designed to foster a culture of collaboration, curiosity, and open communication. Rapid career advancement for driven performers. Access to scientific conferences all over the country throughout the year. A range of amenities, courtesy of the Menlo Park Labs business park, including shuttle, gym, rock-climbing wall, pool, sports courts, cafe, bike lockers, and free EV charging stations. Opportunities to engage with the Hexagon community through team-building events like our Hexagon Happy Hour and holiday parties. Additional Information: The salary range is dependent on the level of experience. The salary range for this position is $140,000 to $165,000 . Our salary ranges are determined by role, level, and location. The range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position across California locations. Within the range, individual pay is determined by work location and additional factors, including job-related skills, experience, and relevant education or training. Hexagon Bio is an equal opportunity employer and committed to a diverse workplace. All applicants will be considered equally without regard to race, color, ethnicity, veteran status, religion, national origin, marital status, political affiliation, age, sex, sexual orientation, disability status, membership in an organization, or any other non-merit factors Note to External Recruiters: Submission of unsolicited resumes prior to an agreement set in place does not create any implied obligation.
Job ID: 484539992
Originally Posted on: 7/9/2025
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