Temporary Research Associate

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We're pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees.

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.

We're building on our rich history, and we believe our greatest achievements are ahead of us. If you're passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!

TEMPORARY RESEARCH ASSOCIATE - LEAD IDENTIFICATION GROUP, ANTISENSE DRUG DISCOVERY

SUMMARY:

Ionis Pharmaceuticals, Inc., a leader in RNA-targeted therapy research and drug discovery, seeks a highly motivated individual to join as a Temporary Research Associate (temp position) in the Antisense Lead Identification team. This is a temporary position with a fixed term of 3-6 months. The role will not be extended beyond 6 months or converted to a permanent position and contract renewal is not anticipated. We are seeking an enthusiastic and self-driven candidate to work in a fast-paced, collaborative, and rewarding environment. In this temporary position the successful candidate will work as a member of the group responsible for in vitro assay development for screening and characterizing oligonucleotides against novel gene targets.

The ideal candidate will have experience in primary and immortalized cells culture and maintenance, with strong aseptic cell culture skills. The candidate should have experience with a broad range of molecular biology techniques and cell-based assays. The candidate should possess a strong work ethic, good communication skills and ideally, experience in an automated high-throughput laboratory environment. The successful candidate will be able to perform the following responsibilities with a high degree of independence and attention to detail.

RESPONSIBILITIES:

Ideal candidate must learn, optimize and meticulously follow preset workflows that has been established to study activity of oligonucleotides. Specific work includes:

• Culture of various mammalian immortalized cell culture systems.
• Ensure maintaining a sterile environment and practicing careful techniques to prevent contamination during cell culture and other downstream processes.
• Perform quality control, feeding, passaging, harvesting and cryopreservation of cells.
• Apply molecular and cell-based assays including but not limited to RNA purification, transfection, and gene expression analysis (RT-qPCR).
• Operate established protocols on automated liquid handling instrumentation and robotics
• Maintain detailed records of experiments

REQUIREMENTS:

• BS./M.S. degree in molecular biology, biology, biochemistry, bioengineering, or related field with demonstrated experience.
• Minimum of 2-3 years' experience working in an academic or industrial laboratory setting.
• Extensive experience and demonstrated expertise in mammalian cell culture is essential.
• Strong molecular biology and assay development skills
• Prior experience with automated instrumentation/liquid handlers for compound screening is desirable
• Ability to work occasional weekend hours as projects demand
• Exceptional attention to detail
• Excellent written and verbal communication skills
• Expected to be a self-starter and work productively within a multidisciplinary team under demanding timelines
• We encourage all highly motivated candidates to apply

For more information about Ionis and to apply for this position, please visit our website, . Reference Requisition #TEMPO003798

The hourly pay scale for this position is $28.34 / hour to $40.42 / hour

NO PHONE CALLS PLEASE. PRINCIPALS ONLY.

Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.