Scientist / Senior Scientist, Cell Biology
- Arrowhead Pharmaceuticals, Inc.
- San Diego, California
- Full Time
The Position
We are seeking a highly motivated and skilled Cell Biologist to join our dynamic research team focused on developing innovative therapeutic strategies. The successful candidate will play a key role in designing and executing cell-based experiments to support platform development and drug discovery initiatives. This role requires strong hands-on experience in mammalian cell culture, cell sorting, and assay development, along with a solid foundation in cell and molecular biology.
Responsibilities
- Design, execute, and interpret in vitro cellular assays to support preclinical research and development
- Maintain and manage various mammalian cell lines under sterile conditions
- Investigate cellular responses to drug candidates, including internalization, trafficking, and downstream signaling
- Participate in development and validation of new drug delivery platform
- Present research findings to cross-function project teams and prepare study reports
- Perform critical experiments with a high level of productivity and scientific rigor
Requirements:
- PhD in biology, bioengineering, biochemistry, or a related field
- Strong expertise in mammalian cell culture and FACS
- Hands-on experience with high-content imaging, automated liquid handling, or screening platforms
- Proficiency in developing and executing endpoint and kinetic assays (e.g., luminescence, fluorescence, activity-based, imaging-based)
- Experience with characterizing ligand-receptor interactions using molecular, cellular, and biochemical approaches
- Proven ability to adapt to fast pace and evolving research priorities
- Track record of scientific productivity, including peer-reviewed publications, conference presentations, or patents
- Additional experience in molecular biology and/or antibody discovery is highly desirable
Preferred
- Industry or postdoc experience