Research Scientist, Functional Assay Development

Labcorp Genetics (formerly Invitae) is dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people!

Our team is driven to make a difference for the patients we serve.

We are leading the transformation of the genetics industry, by making clinical-grade genetic information affordable and accessible to guide health decisions across all stages of life.

We have an excellent career opportunity for a Research Scientist Assay Development to join our growing team in San Francisco, CA!

This position is not eligible for visa sponsorship

Position Summary

The Genetic Insights Group is a team of biologists, machine learning engineers, and clinical geneticists who develop tools to define variant effects. We are hiring a Research Scientist for functional assay development to support the Cellular Evidence Platform (CEP), a quantitative, scalable, and mechanistic assay that generates novel insight into how genetic variation may impact human health. The successful candidate will have extensive expertise in functional genomics in mammalian systems, proficiency with handling, processing, and interpreting large bioinformatic datasets, an enthusiasm for working in collaborative and cross-disciplinary environments, and a strong interest in applying the power of genetics to advance personalized medicine.

Responsibilities:

• Foster a continually developing understanding of the practice and promise of functional variant modeling

• Execute the CEP workflow, including variant library cloning, cell engineering, single-cell capture and cDNA synthesis, library preparation and sequencing, and data processing

• Creatively troubleshoot challenges with the experimental platform

• Collaborate with a cross-functional group of scientists, bioinformaticians, software engineers, and product managers

• Contribute to the management and maintenance of the research and tissue culture labs

• Communicate results to project leaders

• Maintain detailed and organized records within our ELN

Requirements:

• PhD degree in biological science

• Technical knowledge of human genetics, next generation sequencing, and bioinformatics

• Deep domain expertise in next-generation sequencing applications, especially scRNA-seq, as well as first-hand experience with multiple sequencing platforms (i.e., Illumina and PacBio)

• Command of all standard molecular biology procedures, including recombinant DNA technologies, cloning, microbiology, and the manipulation and quantification of gene expression

• Bioinformatic skills sufficient for running the scripts that transfer and process large datasets

Preferred Qualifications:

• Meticulous, creative and independent scientist with a proven track record of applying functional genomics technologies in mammalian cell systems

• Exceptional capabilities in mammalian tissue culture. Experience includes human iPSCs and immune cell types.

• Ability to use Python to run and debug bioinformatics pipelines for single-cell data analysis

• Effective communication and presentation skills within the project team and to stakeholders

• Dedicated commitment to advancing our multidisciplinary teams objectives

Pay Range: $130k - $150k annual salary (USD)

All job offers will be based on a candidates skills and prior relevant experience, applicable degrees/certifications, as well as internal equity and market data.

The position is also eligible for an annual bonus under the Labcorp Bonus Plan. Bonuses are payable based on corporate and/or business segment performance and are subject to individual performance modifiers.

Benefits: Employees regularly scheduled to work 20 or more hours per week are eligible for comprehensive benefits including: Medical, Dental, Vision, Life, STD/LTD, 401(k), Paid Time Off (PTO) or Flexible Time Off (FTO), Tuition Reimbursement and Employee Stock Purchase Plan. Casual, PRN & Part Time employees regularly scheduled to work less than 20 hours are eligible to participate in the 401(k) Plan only. For more detailed information, please click here .

Why People choose to work at Labcorp:
At Labcorp, it is our people that make us great it is what our clients, our partners and, most importantly, what our employees say. Here, you will have the opportunity to collaborate with extraordinary people with diverse viewpoints. You will discover your own outstanding potential as we build an even stronger organization with industry leaders from early development to the clinic and beyond. We help our clients develop medicines that improve health and improve lives of their family and friends.

Labcorp is proud to be an Equal Opportunity Employer:

Labcorp strives for inclusion and belonging in the workforce and does not tolerate harassment or discrimination of any kind. We make employment decisions based on the needs of our business and the qualifications and merit of the individual. Qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, or related medical conditions), family or parental status, marital, civil union or domestic partnership status, sexual orientation, gender identity, gender expression, personal appearance, age, veteran status, disability, genetic information, or any other legally protected characteristic. A dditionally, all qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law.

We encourage all to apply

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