Pharmacology Research Scientist, Ex Vivo

  • Vertex Pharmaceuticals Incorporated
  • Boston, Massachusetts
  • Full Time

Job Description
General Summary:

The CGT Pharmacology group in Boston is seeking a highly motivated and innovative Pharmacology Research Scientist to work collaboratively across the Research organization by supporting pharmacology efforts to understand the pharmacokinetics, pharmacodynamics, and efficacy of novel cell and gene therapies in disease models. The successful candidate will focus on developing, optimizing and validating PK/PD assays, immunoassays, custom multiplexes, and primary cell/explant assays supporting both early discovery and IND-enabling phases. This role requires a specialized technical expert in assay development (e.g. immunoassays, cell assays, flow assays, etc.) who can lead work streams, prioritize data integrity/documentation and mentor others within the team. Strong technical and problem-solving skills, self-motivation, presentation/communication skills, and the ability to both leads, as well as thrive as part of a team are essential.

Key Duties and Responsibilities:

Designs, optimizes and executes preclinical PK, and immunoassay and cell assays to support pharmacology research efforts

Uses a high level of scientific judgment and creative thinking to adapt and/or create standardized workflows & protocols by applying breadth of knowledge and prior work experience.

Takes ownership of daily tasks, researching answers and contacting other subject matter experts independently before soliciting support from senior team members.

Exercises emerging judgment to prioritize workload, based on project impact.

Communicate and work collaboratively within and across functions to support programs from early discovery through preclinical proof of concept and candidate selection to advance the company pipeline.

Authors and reviews Bioanalytical reports for regulatory filings

Analyze, interpret, and present experimental data to project teams and senior leadership.

Possesses a strong understanding of the drug development process and showcases enterprise thinking.

Knowledge and Skills:

Proven technical prociency and demonstrated skill in planning and interpreting experiments, including the measurement of the... For full info follow application link.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Human Resources at ....

Job ID: 521927877
Originally Posted on: 5/21/2026

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