Staff Research Associate
- University of California - San Francisco Campus and Health
- San Francisco, California
- Full Time
Staff Research Associate
University of California - San Francisco Campus and Health
United States, California, San Francisco
Jun 03, 2025
Staff Research Associate
Microbiology and Immunology
Full Time
84439BR
Job Summary
The Staff Research Associate engages in extensive in vitro and in vivo studies of next generation T cell therapies for solid tumors. These studies will include molecular biology (cloning), gene-editing and viral and non-viral transduction of T cells, cell culture, engineered T cell activity (CAR T, TCR T etc) assays (cytotoxicity, proliferation, cell phenotype assessment via flow), in vivo assessment of cell therapies in xenograft and syngeneic settings and general lab support to maintain critical reagents. In vivo work will include tail vein injections of engineered T cells and subcutaneous or intraperitoneal injections of tumor cells into NSG mice or immuncompetent mice (syngeneic mouse tumor models). For all studies, tumor growth will be assessed via bioluminescence or caliper. T cells and tumor cells will also be collected from peripheral blood, tissue, and tumor samples to analyze cell numbers and phenotyping will be performed via flow cytometry and next-generation sequencing.
The final salary and offer components are subject to additional approvals based on UC policy.
Your placement within the salary range is dependent on a number of factors including your work experience and internal equity within this position classification at UCSF. For positions that are represented by a labor union, placement within the salary range will be guided by the rules in the collective bargaining agreement.
The salary range for this position is $28.04 - $45.09 (Hourly Rate).
To learn more about the benefits of working at UCSF, including total compensation, please visit:
Department Description
The Department of Microbiology & Immunology is a basic science department within the School of Medicine (SOM). We perform scientific research and training. ROYBAL LAB / MICROBIOLOGY & IMMUNOLOGY In the Roybal Lab, we harness the tools of synthetic and chemical biology to enhance the therapeutic potential of engineered immune cells. We take a comprehensive approach to cellular engineering by developing new synthetic receptors, signal transduction cascades, and cellular response programs to enhance the safety and effectiveness of adoptive cell therapies.
Required Qualifications
BA/BS in a related science and one or more years of recent, directly related work experience following degree completion, utilizing the techniques or methods required by the position; and/or an equivalent combination of education and experience
Demonstrated ability to work in a team
Communication and organizational skills
Excellent demonstrated record of attendance and punctuality
Accuracy and attention to details
Independence and initiative in problem solving
Ability to adhere to all campus safety policies
Ability to multi task effectively
Analytical skills
Experience with cell culture, molecular and biochemistry assays including cloning, PCR, flow cytometry, ELISA, incucyte. In vivo mouse work including tumor measurements and subcutaneous injections.
Preferred Qualifications
Experience with in vivo mouse work including tail veil, retro-orbital and intraperitoneal injections
About UCSF
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.
Pride Values
UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values.
In addition to our PRIDE values, UCSF is committed to equity - both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu
Join us to find a rewarding career contributing to improving healthcare worldwide.
Equal Employment Opportunity
The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.
Organization
Campus
Job Code and Payroll Title
009617 SRA 2 NEX
Job Category
Research and Scientific
Bargaining Unit
University Professional Technical Employees - Research Support Professionals Unit (UPTE-RX)
Employee Class
Career
Percentage
100%
Location
San Francisco, CA
Campus
Parnassus Heights (SF)
Work Style
Fully On-Site
Shift
Days
Shift Length
8 Hours
University of California - San Francisco Campus and Health
United States, California, San Francisco
Jun 03, 2025
Staff Research Associate
Microbiology and Immunology
Full Time
84439BR
Job Summary
The Staff Research Associate engages in extensive in vitro and in vivo studies of next generation T cell therapies for solid tumors. These studies will include molecular biology (cloning), gene-editing and viral and non-viral transduction of T cells, cell culture, engineered T cell activity (CAR T, TCR T etc) assays (cytotoxicity, proliferation, cell phenotype assessment via flow), in vivo assessment of cell therapies in xenograft and syngeneic settings and general lab support to maintain critical reagents. In vivo work will include tail vein injections of engineered T cells and subcutaneous or intraperitoneal injections of tumor cells into NSG mice or immuncompetent mice (syngeneic mouse tumor models). For all studies, tumor growth will be assessed via bioluminescence or caliper. T cells and tumor cells will also be collected from peripheral blood, tissue, and tumor samples to analyze cell numbers and phenotyping will be performed via flow cytometry and next-generation sequencing.
The final salary and offer components are subject to additional approvals based on UC policy.
Your placement within the salary range is dependent on a number of factors including your work experience and internal equity within this position classification at UCSF. For positions that are represented by a labor union, placement within the salary range will be guided by the rules in the collective bargaining agreement.
The salary range for this position is $28.04 - $45.09 (Hourly Rate).
To learn more about the benefits of working at UCSF, including total compensation, please visit:
Department Description
The Department of Microbiology & Immunology is a basic science department within the School of Medicine (SOM). We perform scientific research and training. ROYBAL LAB / MICROBIOLOGY & IMMUNOLOGY In the Roybal Lab, we harness the tools of synthetic and chemical biology to enhance the therapeutic potential of engineered immune cells. We take a comprehensive approach to cellular engineering by developing new synthetic receptors, signal transduction cascades, and cellular response programs to enhance the safety and effectiveness of adoptive cell therapies.
Required Qualifications
BA/BS in a related science and one or more years of recent, directly related work experience following degree completion, utilizing the techniques or methods required by the position; and/or an equivalent combination of education and experience
Demonstrated ability to work in a team
Communication and organizational skills
Excellent demonstrated record of attendance and punctuality
Accuracy and attention to details
Independence and initiative in problem solving
Ability to adhere to all campus safety policies
Ability to multi task effectively
Analytical skills
Experience with cell culture, molecular and biochemistry assays including cloning, PCR, flow cytometry, ELISA, incucyte. In vivo mouse work including tumor measurements and subcutaneous injections.
Preferred Qualifications
Experience with in vivo mouse work including tail veil, retro-orbital and intraperitoneal injections
About UCSF
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.
Pride Values
UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values.
In addition to our PRIDE values, UCSF is committed to equity - both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu
Join us to find a rewarding career contributing to improving healthcare worldwide.
Equal Employment Opportunity
The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.
Organization
Campus
Job Code and Payroll Title
009617 SRA 2 NEX
Job Category
Research and Scientific
Bargaining Unit
University Professional Technical Employees - Research Support Professionals Unit (UPTE-RX)
Employee Class
Career
Percentage
100%
Location
San Francisco, CA
Campus
Parnassus Heights (SF)
Work Style
Fully On-Site
Shift
Days
Shift Length
8 Hours
Job ID: 480092248
Originally Posted on: 6/6/2025
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