Molecular Laboratory Technician

JOB TITLE: Molecular Laboratory Technician

LOCATION: Full-time onsite position at our K2 Bio Lab Facility in Houston, TX

Address:

2710 Reed Road, Suite 160

Houston, TX 77051

About the Company:

Plus Therapeutics, Inc.
Plus Therapeutics, Inc. is a publicly traded (Nasdaq: PSTV), clinical-stage pharmaceutical company focused on developing novel targeted radiotherapeutics for patients with difficult-to-treat cancers of the central nervous system. The companys therapies aim to improve quality of life and extend survival. Plus is advancing a robust pipeline of drug candidates, with lead programs in recurrent glioblastoma (GBM) and leptomeningeal metastases (LM).

CNSide Diagnostics, LLC
CNSide Diagnostics, LLC is a subsidiary of Plus Therapeutics, Inc., dedicated to developing and commercializing proprietary clinical diagnostic laboratory assays, such as CNSide . This assay is designed to detect tumor cells that have metastasized to the central nervous system in patients with carcinomas and melanomas.

CNSide enables quantitative analysis and molecular characterization of tumor cells and circulating tumor DNA in the cerebrospinal fluid, helping to inform and improve clinical management. The company is on track to commercialize CNSide in the U.S.

Job Summary:

We are seeking a skilled molecular technician with at least two years of experience working in a high-complexity laboratory to join our team. The ideal candidate will have previous experience working in a clinical laboratory and familiarity with clinical regulatory agency standards. This role requires technical expertise in molecular biology techniques, focused attention on quality control standards and technical detail, and the ability to work in a fast-paced environment.

Key Responsibilities:

• Perform various molecular and immunocytochemistry tests including ICC, FISH, NGS, etc. for clinical, research, or diagnostic applications
• Analyze and interpret assay results, troubleshoot technical issues, and document findings
• Participate in validation and verification studies for new assays and instrumentation
• Perform quality control and quality assurance (QA/QC) procedures to ensure test accuracy and reproducibility
• Navigate and complete tasks assigned by laboratory supervisor
• Monitor and record environmental conditions in the laboratory on a daily, weekly and monthly basis
• Monitor and record equipment calibration and maintenance records
• Monitor and perform equipment maintenance requirements as needed
• Monitor and track laboratory inventory and submit purchase orders for reagents and consumables
• Collaborate with senior scientists and other team members to optimize workflows and improve efficiency
• Follow clinical standard operating procedures (SOPs) while maintaining compliance with CLIA, COLA, and/or CAP regulations

Job Requirements:

• Educational Background : Bachelors degree in laboratory medicine (preferred), molecular biology, biology, biochemistry, genetics, or a related field
• Experience : Two or more years of hands-on experience working in a clinical diagnostic, forensic or research laboratory
• Operational and Technical Expertise : Familiarity with maintaining laboratory inventory and reagent fabrication as well as knowledge of clinical trial operations and logistics procedures
• Analytical and Problem-Solving Skills : Strong analytical capabilities and a proactive approach to problem-solving with a focus on operational efficiency and quality improvement.
• Regulatory Knowledge : Familiarity with clinical laboratory regulatory requirements (CLIA, COLA and/or CAP) and with maintaining compliance

Preferred Qualifications

• Experience performing ICC, FISH, NGS and related assays
• MLT (medical laboratory technician) or MT (medical technologist)
• Experience with good manufacturing practices (GMP)
• Authorship or support for the development of laboratory SOPs
• Knowledge of bioinformatics tools and software as well as LIMS and eQMS platforms
• Team player

Skills and Abilities:

• Excellent presentation and communication skills written, verbal and interpersonal.
• Proficiency in Microsoft Office 365
• Manage multiple complex projects simultaneously.
• Excel within a cross-functional and fast-paced environment.
• Strong critical thinking skills.
• Focus on execution and results.
• High level of professionalism, quality, and teamwork.

Work Environment:

• The essential functions of the job are usually performed in an environmentally controlled facility where the noise level in the work environment is usually moderate. This position may involve a combination of office and laboratory environments and automated equipment.
• While performing the job duties, the employee is regularly required to sit; reach with hands and arms and talk or hear. The employee is frequently required to stand and walk. The employee may sometimes be required to lift and/or move up to 25 pounds. Specific vision abilities required by this job include close vision, distance vision, color vision and ability to adjust focus. The employee must have manual dexterity and the ability to effectively use computer terminals.

Equal Employment Opportunity

Plus Therapeutics, Inc. provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, disability, genetic information, marital status, amnesty, or status as a covered veteran in accordance with applicable federal, state and local laws.

Additional Benefits:

• Medical
• Dental
• Vision
• Life and Disability Insurance
• 401k with Company Match
• as well as additional benefits

Compensation: Commensurate with background and experience.

• Educational Background : Bachelors degree in laboratory medicine (preferred), molecular biology, biology, biochemistry, genetics, or a related field
• Experience : Two or more years of hands-on experience working in a clinical diagnostic, forensic or research laboratory
• Operational and Technical Expertise : Familiarity with maintaining laboratory inventory and reagent fabrication as well as knowledge of clinical trial operations and logistics procedures
• Analytical and Problem-Solving Skills : Strong analytical capabilities and a proactive approach to problem-solving with a focus on operational efficiency and quality improvement.
• Regulatory Knowledge : Familiarity with clinical laboratory regulatory requirements (CLIA, COLA and/or CAP) and with maintaining compliance

Preferred Qualifications

• Experience performing ICC, FISH, NGS and related assays
• MLT (medical laboratory technician) or MT (medical technologist)
• Experience with good manufacturing practices (GMP)
• Authorship or support for the development of laboratory SOPs
• Knowledge of bioinformatics tools and software as well as LIMS and eQMS platforms
• Team player
• Excellent presentation and communication skills written, verbal and interpersonal.
• Proficiency in Microsoft Office 365
• Manage multiple complex projects simultaneously.
• Excel within a cross-functional and fast-paced environment.
• Strong critical thinking skills.
• Focus on execution and results.
• High level of professionalism, quality, and teamwork.