Senior Scientist I, Immuno-Pharmacology

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

We are seeking a Senior Scientist I with a strong background in immunology and/or peptide biology to join AbbVie's Immunology Discovery organization within the Immuno-Pharmacology and Peptide Discovery department. This lab-based role supports both IND-enabling and early-stage discovery programs, as well as peptide platform research and innovation. It involves hands-on experimentation in autoimmune disease models and translational in vitro assays, including the development of novel assays to evaluate peptide therapeutics. You will develop and implement novel experimental approaches to address key scientific questions in peptide immunology. Investigate, identify, and optimize new methods, assays, and techniques relevant to peptide therapeutic discovery and immunological mechanism of action. Offer scientific insights to projects, particularly in areas such as inflammatory pathways, immune cell trafficking, immune receptor modulation, receptor targeting, target density in tissues, and receptor occupancy. Collaborate effectively with cross-functional teams (e.g., in vivo pharmacology, DMPK, and platform groups) to drive technical problem-solving and ensure cohesive integration of efforts across projects.

Responsibilities:

• Innovative Research & Method Development: Consistently demonstrate scientific initiative and creativity by exploring novel experimental approaches and developing new immunological methods to address complex research questions.
• Autonomous Experimental Design & Troubleshooting: Operate with a high degree of autonomy in the lab, independently designing experiments and troubleshooting technical challenges with minimal supervision, while maintaining rigorous scientific standards supporting peptide therapeutic programs and platform.
• Immunological Assays & Complex Cellular Systems: Design and execute a broad range of immunological assays (e.g., ELISPOT, cytokine profiling, cellular potency assays, whole blood assays) and utilize complex cellular systems to characterize immune responses to peptide therapeutics.
• PK/PD Relationship: